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首页 > Products > Reagents > Cervical Cancer Biomarker Diagnostic Kits > E7-IHC (E7 Immunohistochemistry)

E7-IHC (E7 Immunohistochemistry)

HPV E7 Protein Detection Kit (IHC)

Antibody: Rabbit monoclonal, Cocktail 1x working solution

Packing Size: 3ml, 6ml, 12ml

Application: IHC test for biopsies or surgical tissue sections for positive expression of E7 protein

Application Range: FFFE specimens (formalin fixed paraffin embedded) from tissue sections

Pre-treatment: Antigen retrieval in Citric acid (PH=6.0) buffer

Consultation

The oncogene E6/E7 carried by the high-risk HPV virus expresses its oncogene products E6 and E7 proteins by integrating into the genome of infected human cells. E6 and E7 proteins play causative roles in transformed human cells, their carcinogenic mechanism had been studied in a vast number of scientific reports. Especially, E7 protein plays a key role in disrupting the signaling pathway for cell cycle, leading to the transformation and tumorigenesis of cervical epithelial cells.
The E7 antibody detection reagent (E7-IHC) works through the antigen-antibody high affinity and specific binding, therefore, detecting cancer cells. E7 positive cells or tissue exhibit brown staining, which can be observed under pathology microscope. E7-IHC positive staining indicates the transformation status in the tissue, and the active growth or the aggressiveness of tumor progression.

Record Certificate

Registration Certificate No:苏苏械备20181131号

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