P16 antibody reagent (immunohistochemistry) is an immunohistochemical reagent, which is used to qualitatively detect p16 protein in formalin fixed and paraffin embedded tissue sections,For tissue or cells staining by immunohistochemical method (IHC) or immunocytochemistry (ICC). Additional to conventional pathology by HE staining.
Packing size: 3 mL,6 mL
The expression of p16 was abnormal in cervical cancer with HPV infection, and its expression was positively correlated with the severity of cervical cancer. In HPV infection related lesions, the E7 protein of the virus interferes with the Rb pathway, leading to the diffuse and consistent expression of p16. At the same time, p16 was expressed in cervical cancer, nasopharyngeal carcinoma, lung cancer, breast cancer, ovarian cancer and lymphoma.
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